Endocrine Abstracts

Hypertension remains one of the most common diseases affecting more than 25% of the whole population. It is associated with high mortality risk due to cardiovascular complications. Usually hypertension is of idiopathic origin, however, several other diseases, including hormonal abnormalities may cause hypertension.Here, we present the frequency of primary hyperaldosteronism in a group of 310 hypertensive patients.Previously, they h...

Carney’s triad is a very rare syndrome, which comprises three tumors of different origin: gastrointestinal stromal tumor (GIST), thoracic chondroma and extraadrenal pheochromocytoma. It is found mainly in young female patients with blood group A. Two of the tumors need to be present for the diagnosis.Here we present the case of a 58-year-old male with blood group B. In July 2004 patient underwent resection of a part of small intestine with two GISTs...

Acromegaly is a chronic disease with typical clinical signs evoked by overproduction of growth hormone (GH) and insulin-like factor 1 (IGF1). It is nearly always caused by somatotroph adenoma which can be visualized by MRI scanning. Other causes of acromegaly are very rare and comprises ectopic secretion of GH or GH-RH by other neoplasms.Here, we present a case of 62-year old acromegalic woman. Acromegaly was firstly diagnosed 9 years ago. Her GH concent...

The most typical signs of Cushing’s syndrome (CS) are easy bruising, hypertension and ‘cushingoid’ phenotype with central deposits of fat tissue. Moreover, hypercortisolemia may affect also reproductive system leading to loss of libido and impotence in men and menstrual disturbances and infertility in women.However, some of the patients remains fertile, although pregnancy is uncommon and is associated with fetal morbidity and mortality in ...

Introduction: Pheochromocytomas are rare neuroendocrine tumors arising from chromaffin cells of the adrenal medulla. Approximately 10% of all pheochromocytomas are malignant. There is no effective therapy for malignant pheochromocytoma (MAL-PHEO) and the overall prognosis is poor.Case report: We report 22-year survival with MAL-PHEO in a patient treated with several surgeries, 131I-metaiodobenzylguanidine and, subsequently, with long-acting fo...